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You have it backwards. In science, observable evidence always comes first, leading to a hypothesis.
No, a scientist may develop a hypothesis based on an event...he/she will try to explain that event. When they have a working hypothesis that might explain it, they will conduct an experiment(s) to see if their hypothesis can be justified
It is the results of these experiments that constitute the "observable evidence"
You have to have a hypothesis first, then the experiment, and from that you get the "observable evidence".