To the thread question, I opted for items 1 through 4 inclusive.
I chose option one because aside from Fox News Media and a small number of newspaper organizations (New York Post, Boston Herald, Las Vegas Review-Journal, Pittsburgh Post Gazette, to name a few) which supported him, only one other major news publication i.e. the Wall Street Journal was at least neutral in its reporting. That left all the other organs of media providing all-hate all-the-time biased/misrepresenting and IMO outright propaganda against him.
I also chose option two because TDS is IMO a very real mental state ingrained as often as not by the vast majority of media organs mentioned above pushing that anti-Trump propaganda.
I also chose option three because it is just a repeat of item 1 above.
I added option four because Mr. Soros funds a vast network of agents in all areas of news media, social media, and politics via bought and paid for politicians and media pundits. IMO he has instructed them to act against anyone, any group, any organization, and any politician that doesn't support his socialist ideology.
That all of the above factors have helped to create and maintain a "Pavlovian" mental state of TDS amongst a large segment of the U.S. population. The sufferers have been literally indoctrinated so deeply that IMO they are simply blind to this reality of themselves. IMO the 60 members who voted "he deserves the criticism" prove my point.