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I'd have you try to explain it too my parents, but they are gone now - they were preceeded in death thanks to a "kid" enjoying his high while missing a stop sign and killing my brother.
If you mean a true Conservative, as in "small government", yes. In that respect, even I am a conservative. But, the vast majority of "conservative" politicians are social conservatives, AKA Authoritarian Liberals. Such liberals are typically not trying to end any government spending.
Studies have shown that people who are going to DWI will tend towards Marijuana instead of Alcohol, if it's legal. Marijuana does impair your driving skills, but not nearly as bad as Alcohol; statistically, marijuana's availability reduces rates of traffic accidents. Why Medical Marijuana Laws Reduce Traffic Deaths | TIME.com
If we could just magically "make" all drugs go away, then we would, but we can't. Prohibition is ignoring the problem, while regulation deals with it. In Portugal's case, they decriminalized all drugs, and still found it to be less harmful than prohibition. Decriminalizing Drugs in Portugal a Success, Says Report - TIME After allowing everything from Marijuana to Heroin, they found that all use dropped, addiction rates dropped, STD rates from needle sharing dropped, Overdoses dropped, total drug related deaths dropped, and teen drug use dropped. It was a complete success. We've seen similar success stories from dozens of countries that have started to reverse drug prohibition, and it's most noticeable for Marijuana.
All places that have legalized, regulated, or decriminalized Marijuana have found that all negative things associated with it start to reduce. Prohibition is the cause of the harm.