The human body has always seen vitamins in the form of micro-nutrients in our food. That's how we digest them. It's not natural, normal or even healthy to segregate those vitamins into their pure chemical compounds and then take massive dosages of them. Vitamins are chemical compound; there's drug interactions, medical side-effects and the
vitamin toxicity is severely taxing on your kidneys and liver. As middle class Americans, we usually get our recommended nutrients and those multivitamin supplements are unnecessary overkill. A single cup of spinach contains almost all of the nutrients your body needs.
That's partially why aspirin is also dangerous. It's a salicylate drug, like salicylic acid, and like large dose vitamins, aspirin is hell on your GI tract and liver. That's why physicians scream about not consuming alcohol with aspirin; they don't want internal bleeding.