Vaccines extremely effective against COVID variants of concern: Canadian study

[Allan]

Very good news and yet another reason to get vaccinated.

Researchers around the world are sifting through data to determine how the leading COVID-19 vaccines are doing against the variants of concern. Now, a big pre-print study from Ontario suggests that the vaccines used in Canada—Pfizer, Moderna and AstraZeneca—are very effective against the four big variants of concern: Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2).

“Our findings suggest that even a single dose of these three vaccine products provides good to excellent protection against symptomatic infection and severe outcomes caused by the four currently circulating variants of concern, and that two doses are likely to provide even higher protection,” the authors concluded. The study’s results showed that being fully vaccinated gives a person roughly the same protection against Delta as Alpha, Beta and Gamma. The data shows that the vaccines are doing even better than previous studies suggested against the variants in terms of symptomatic infection as well as hospitalization and death.

Link

 

[Callen]

Great news! Not sure why some are willing to spin the roulette wheel with their health and even their lives. We are at 78% at one shot and I believe 45% at fully vaxxed and suspect we will easily top 80%. I really want the border to open but I suspect it won't this month.

 

[tshade]

Very good news and yet another reason to get vaccinated.



Link

Yeah, that's great. NOW, do they have a vaccine that cures "anti-vaxer" stupidity = THAT is the REAL danger.....

 

[RAMOSS]

Very good news and yet another reason to get vaccinated.



Link

Well, some little disappointment there. According to the real world numbres in Israel, the Pfizer vaccine fades quickly against the delta variant.

Pfizer vaccine protection takes a hit as Delta variant spreads, Israeli government says | CNN

The Israeli government says its analysis has shown the Pfizer-BioNTech coronavirus vaccine appears to be less effective against infections caused by the Delta variant compared to other strains of Covid-19.

www.cnn.com

 

[Ethel2]

Well, some little disappointment there. According to the real world numbres in Israel, the Pfizer vaccine fades quickly against the delta variant.

Pfizer vaccine protection takes a hit as Delta variant spreads, Israeli government says | CNN

The Israeli government says its analysis has shown the Pfizer-BioNTech coronavirus vaccine appears to be less effective against infections caused by the Delta variant compared to other strains of Covid-19.

www.cnn.com

The question is will it still keep people out of the hospital. And is it a matter of producing 5x as much antibody as you need vs 10x. From what I have been reading the people getting hospitalized are covidiots, not normal people who have done the right thing.
No major cause for concern yet. At worse a booster may be needed, which is fine with me.

 

[RAMOSS]

The question is will it still keep people out of the hospital. And is it a matter of producing 5x as much antibody as you need vs 10x. From what I have been reading the people getting hospitalized are covidiots, not normal people who have done the right thing.
No major cause for concern yet. At worse a booster may be needed, which is fine with me.

That is not the case in Israel. It appears for the delta variation, and the pfizer vaccine, the efficency went down from 95% to 65% in just a few months. It's something to be aware of, and monitored. I suspect there will be a pfizer booster against the delta variant by fall.

 

[MaryP]

That is not the case in Israel. It appears for the delta variation, and the pfizer vaccine, the efficency went down from 95% to 65% in just a few months. It's something to be aware of, and monitored. I suspect there will be a pfizer booster against the delta variant by fall.

Huh. Sounds right--booster coming.

Well, some little disappointment there. According to the real world numbres in Israel, the Pfizer vaccine fades quickly against the delta variant.

Pfizer vaccine protection takes a hit as Delta variant spreads, Israeli government says | CNN

The Israeli government says its analysis has shown the Pfizer-BioNTech coronavirus vaccine appears to be less effective against infections caused by the Delta variant compared to other strains of Covid-19.

www.cnn.com

It's still highly effective against serious cases. From your link:

The government added that the vaccine was now 93% effective in preventing severe disease and hospitalizations, compared to 97% reported in the medical journal The Lancet in May.

That's still very good protection. They're saying, If you're vaccinated, don't worry. Remember , 'cases' can be totally asymptomatic or mild, not just serious illness. They didn't mention hospitalizations and deaths in the article, did they? They were saying the same thing about the Moderna, Pfizer and J&J vaccines when they first rolled out, but from the experience being reported by hospitals, they are actually performing better than predicted.

 

[RAMOSS]

Huh. Sounds right--booster coming.

It's still highly effective against serious cases. From your link:

The government added that the vaccine was now 93% effective in preventing severe disease and hospitalizations, compared to 97% reported in the medical journal The Lancet in May.

That's still very good protection. They're saying, If you're vaccinated, don't worry. Remember , 'cases' can be totally asymptomatic or mild, not just serious illness. They didn't mention hospitalizations and deaths in the article, did they? They were saying the same thing about the Moderna, Pfizer and J&J vaccines when they first rolled out, but from the experience being reported by hospitals, they are actually performing better than predicted.

Yes, but it still dropped, and the infection protectoin went from the 90's to mid 60's.

It's something to keep on eye on.

it's not horrible, just something to keep track of. If the local numbers in your area go up, and it is delta variant heavy, it would be time to take extra precautions if you got the Pfizer vaccine.

 

[MaryP]

Yes, but it still dropped, and the infection protectoin went from the 90's to mid 60's.

It's something to keep on eye on.

it's not horrible, just something to keep track of. If the local numbers in your area go up, and it is delta variant heavy, it would be time to take extra precautions if you got the Pfizer vaccine.

I got the Moderna, no numbers out on that yet that I know of. However, thanks for the heads up!

 

[Ethel2]

That is not the case in Israel. It appears for the delta variation, and the pfizer vaccine, the efficency went down from 95% to 65% in just a few months. It's something to be aware of, and monitored. I suspect there will be a pfizer booster against the delta variant by fall.

Efficacy related to symptomatic disease? Or efficacy related to hospitalization and death?
I think what most people are concerned about is the latter. If a booster is needed to cover existing variants it will be because the vaccine isn’t keeping people out of the hospital.
I am personally fine with a booster. Its no big deal. The mRNA vaccines have proven very safe.

 

[RAMOSS]

Efficacy related to symptomatic disease? Or efficacy related to hospitalization and death?
I think what most people are concerned about is the latter. If a booster is needed to cover existing variants it will be because the vaccine isn’t keeping people out of the hospital.
I am personally fine with a booster. Its no big deal. The mRNA vaccines have proven very safe.

Symptatic disease. The effectiveness for preventing hospitalization went from 98% to 93%. Not much of a drop, but still somtething to keep on eye on

 

[Ethel2]

Symptatic disease. The effectiveness for preventing hospitalization went from 98% to 93%. Not much of a drop, but still somtething to keep on eye on

If those stats hold up I think a booster is a good idea.
JMO

 

[TU Curmudgeon]

Great news! Not sure why some are willing to spin the roulette wheel with their health and even their lives. We are at 78% at one shot and I believe 45% at fully vaxxed and suspect we will easily top 80%. I really want the border to open but I suspect it won't this month.

BC is at 79.22% (people 12+ years old) and 70.7 (total population) for "single dose" and at 37.46% (people 12+ years old) and 33.13% (total population) for "full vaccination"

 

[TU Curmudgeon]

That is not the case in Israel. It appears for the delta variation, and the pfizer vaccine, the efficency went down from 95% to 65% in just a few months. It's something to be aware of, and monitored. I suspect there will be a pfizer booster against the delta variant by fall.

If you get enough of the population vaccinated fast enough, then you break the infection cycle since there aren't enough infected people floating around to re-infect a significant portion of the population.

If you don't, you don't.

 

[RAMOSS]

If you get enough of the population vaccinated fast enough, then you break the infection cycle since there aren't enough infected people floating around to re-infect a significant portion of the population.

If you don't, you don't.

The key here is the weakening of the vaccine might change how many you need to vaccinate to break the cycle

 

[TU Curmudgeon]

The key here is the weakening of the vaccine might change how many you need to vaccinate to break the cycle

Then vaccinate more and faster.