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Some data for you. From the National Institute of Health.
pmc.ncbi.nlm.nih.gov
Approximately 58% of transgender patients had at least one DSM-5 diagnosis compared with 13.6% of cisgender patients (p<0.0005). Transgender patients had increased prevalence for all psychiatric diagnoses queried (Table 1), with major depressive disorder and generalized anxiety disorder being the most common diagnoses (31% and 12%, respectively). There was also an increased lifetime prevalence of bipolar disorder (11%) and psychotic disorders (4.7% overall, 2.5% for schizophrenia and 2.2% for schizoaffective disorder) in transgender adults. Ten percent of transgender adults had a history of a substance use disorder, including 4.2% for alcohol and 3.8% for cannabis.
Mental Health Diagnoses Among Transgender Patients in the Clinical Setting: An All-Payer Electronic Health Record Study - PMC
We performed a cross-sectional analysis of the prevalence of psychiatric diagnoses among transgender patients in clinical care using an all-payer electronic health record database. Of 10,270 transgender patients identified, 58% (n=5940) had at least ...

Approximately 58% of transgender patients had at least one DSM-5 diagnosis compared with 13.6% of cisgender patients (p<0.0005). Transgender patients had increased prevalence for all psychiatric diagnoses queried (Table 1), with major depressive disorder and generalized anxiety disorder being the most common diagnoses (31% and 12%, respectively). There was also an increased lifetime prevalence of bipolar disorder (11%) and psychotic disorders (4.7% overall, 2.5% for schizophrenia and 2.2% for schizoaffective disorder) in transgender adults. Ten percent of transgender adults had a history of a substance use disorder, including 4.2% for alcohol and 3.8% for cannabis.