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Improving on Nature: Coelenterazine & a simplified analog

JacksinPA

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Coelenterazine (compound A in the attached graphic) is a component of bioluminescent systems in a wide range of marine organisms. See https://en.wikipedia.org/wiki/Coelenterazine. Interestingly, a Japanese research group found in 1991 that this large molecule can be significantly reduced in size & complexity (compound B) while still generating light when oxidized by the enzyme luciferase.

Coelenterazine.jpg
 
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