Second, the polarization on religion largely comes about from the Republicans' politicizing it, since Reagan's building of the 'religious right', intentionally trying to convert as many Christians as possible to support Republicans, by pandering to them on any number of issues they could find.
The people who have threatened the 'freedoms' the most on religious issues have been these Republican religious voters - who, for example, made one of their most important issues for a long time preventing gay people from being able to get married. They've also tried to make 'the right to discriminate' into a right for themselves, under the name of 'religious liberty'. So, for example, if they refuse to hire gay workers, that's not discrimination against gays - it's just THEIR religious freedom, and any limits on their discriminating are denying THEM rights. There's seemingly no end to the ways the manipulators find to convince these targeted 'religious right' voters that they are victims of Democrats, to pander to them, to get their votes.
Thirdly, this polarization DOES create some increased conflicts. The more 'religious right' voters hate Democrats as you describe above, and the more they vote for right-wing policies as a result such as allowing the oil companies to pollute more or to leave people without healthcare, the more Democrats do resent them. The more they fall for con jobs, the more Democrats do resent that.
It's not mistreating them for their religion, so much as disliking their falling for the 'religious right' con and supporting Republican politics that are harmful.
Most of the things I see the religious right people think about Democrats are wrong - hyped fears that are lies fed to them by propagandists. Some differences are real - abortion, gay marriage, etc. But many are lies and exaggerations. There has been a real effort to create this divide for the benefit of the wealthy Republican interests, by using issues to polarize.
Really, religious values are a lot more aligned with *Democrats* for the most part.
It's not easy to tell people who have been conned, that they have - people don't like to admit they were. So the more Democrats say, 'you are being conned', the more the people who have been conned think that just proves Democrats are looking down on them.
Democrats are more likely to feel smart and superior, even if they aren't. They are more likely to see themselves as kindhearted and generous, even if they aren't. They are more likely to believe that Big Science has, or can find, all the answers.
That's really a lot of emotional stuff that isn't what votes should be based on - it's the stuff of propaganda used to get you to vote the way other interests want you to.
As far as science - on that we might disagree. Again, you weren't very specific.
But when science said cigarettes are killing people, big tobacco donated to Republicans who spent decades saying 'the science isn't settled', protecting tobacco companies in Republican states.
When science said manmade activities, mostly fossil fuel use, filling the atmosphere with too much carbon are going to cause great harm to the climate, the huge companies who profit from the use of fossil fuels paid Republicans to deny the science.
So I'm not sure what you are citing specifically - but as I type, the corrupt trump administration is destroying the government's scientific capabilities to serve these corrupt interests, ordering the USDA scientists to relocate to Kansas - it's estimated 90% will resign. Problem of 'science' and pesky science talking about the climate solved.
If you are against that science, then Republicans are your party. But why would be be against the science?
I'd encourage you not to vote based on 'emotion' and manipulations to get you to resent other people, but on issues and policies and who serves your interests and the good of the country. Republicans are basically 100% corrupt as a party in who they serve, and they use pandering to try to get votes. There's a high cost to people either falling for their cons or voting based on the pandering.
They might get a politician who hates gay marriage the way they like, but who votes for trillions of more dollars to get to the rich, instead of the American people, as the price.
3/3