The only pathetic thing is to believe that there is no prejudice and there is just a difference of opinions! The latter CAN be a sign of prejudice
If I think you are a piece of s*** because of your sexual orientation, or of what you do in your personal life, even though your actions do not harm me or other people, this is prejudice. If I disagree with a neoNazi regarding if the Jews in Germany were vermin or not , this does not mean that there is no prejudice, and there is just a difference of opinions between me and him!
Yes, we have read that many transexuals have psychological issues and a high rate of suicides, but social rejection and prejudice may be at the root of that problem, and we have the responsibility to treat them in the same way we treat the white straight guys who f** up their life with painkillers, alcohol and opioids.
When prominent Evangelical leaders spread rumors that gays use rings to prick our fingers and transmit AIDS to us, or when asshole Christians (in the same video I posted earlier) are concerned about transferring in a car a person who has Aids (but never seem to worry of transferring a person who has hepatitis), it is obvious that some people have cultivated an unreasonable level of fear of gays and transexuals.
Such "difference of opinions" about how dangerous or corrupt are certain people are often clear signs of prejudice unless the accusers can show clear evidence that gays and transexuals are really dangerous to the rest of us because if they cannot provide such evidence, then I do not see why a straight person should be more concerned about the safety of his family from the danger of gays than from the danger of Catholics who cannot address pedophilia.