For people who wear a cumbersome mask to bed to avoid the life-threatening, long-term effects of a serious breathing disease, the prospect of shedding the headgear for a single pill taken at bedtime has been the stuff of dreams.
Now, those dreams appear likely to become reality for at least some people with obstructive sleep apnea (OSA), who stop breathing dozens or hundreds of times during the night, causing their blood oxygen to drop before they subconsciously awake. Top-line results from a large clinical trial, released this week, showed a combination of two medications in one pill stimulates muscles that keep the airway open, sharply decreasing breathing disruptions.
“It’s pretty clear that this medication combination is reducing obstructive sleep apnea events. And it’s reducing the severity of oxygen drops during sleep. That is exciting,” says Sigrid Veasey, a sleep physician and neuroscientist at the University of Pennsylvania who was not involved with the study. “The effects are robust and have a good scientific basis,” she says.
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However, physicians have questions about the drug that Apnimed’s press release didn’t address. For one, it’s unclear whether the drug affects patients’ actual symptoms, such as daytime sleepiness, says Najib Ayas, a sleep physician at the University of British Columbia who was the principal investigator at one of the sites in the current trial. “You want the patients to feel better with therapy, not only to have a reduction in [airway obstructing events],” he says.
I think you should find another thread for this nonsense.BUT.................................. science and drugs can't be trusted, they may cause autism. So I've heard. Especially if it's a NEW drug, we won't know the long term effects, or if they alter our DNA.
I think we would need to consult with RFKJr. before we put too much faith into this new drug.
I was just curious why THIS new drug is so exciting when OTHER drugs are considered dangerous.I think you should find another thread for this nonsense.
Please post where I’ve said anything remotely related to what you’re talking about.I was just curious why THIS new drug is so exciting when OTHER drugs are considered dangerous.
BUT.................................. science and drugs can't be trusted, they may cause autism. So I've heard. Especially if it's a NEW drug, we won't know the long term effects, or if they alter our DNA.
I think we would need to consult with RFKJr. before we put too much faith into this new drug.
I think you should find another thread for this nonsense.
Sure, but the Secretary really has the final say (except for the President) on whether to accept their recommendations or not.
One of the medications, atomoxetine, approved by the U.S. Food and Drug Administration (FDA) in 2002 for attention-deficit/hyperactivity disorder
Yeah, that was my first question when I read the article as well. They obviously haven’t researched all of the potential side effects.Sounds promising. Many medications to alleviate breathing issues are stimulants – which is not exactly conducive to sleep. Hopefully they have found a combination that will work for most people.
That remains to be seen. Since this drug is in the early stages of testing, it probably won’t be ready to seek approvals for a few years.Hmm…
This is a medication utilized for ADHD currently.
Have a feeling this won’t go anywhere until this administration is no longer in power. I highly doubt they’ll be approving anything regarding ADHD medications for any sort of expanded use
Yeah, I asked my pulmonologist about the surgery some years ago and he wouldn’t recommend it. Said the results weren’t that predictable and the recovery was awful.I find the commercials for the surgery to be tres creepy.
But a pill? Hmm.
They have the final say on what does/does not get FDA approval.That remains to be seen. Since this drug is in the early stages of testing, it probably won’t be ready to seek approvals for a few years.
BTW, nothing of the post you brought over from the thread about RFK Jr telling people to not take medical advice from him contradicts anything I’ve said in this thread.
and a garage clicker to go to sleep, nah, thanks, but nah.Yeah, I asked my pulmonologist about the surgery some years ago and he wouldn’t recommend it. Said the results weren’t that predictable and the recovery was awful.
THAT was the point I was trying to make. But apparently it was confusing.Have a feeling this won’t go anywhere until this administration is no longer in power. I highly doubt they’ll be approving anything regarding ADHD medications for any sort of expanded use. RFK Jr and his FDA, etc are trying to blame vaccines, medications, etc for an “epidemic” they say exists…and you think they’re going to expand the utilization of ADHd drugs for other purposes?
There’s nothing confusing about your constant trolling.THAT was the point I was trying to make. But apparently it was confusing.
Your own article said they were hoping to seek FDA approval in 2026Since this drug is in the early stages of testing, it probably won’t be ready to seek approvals for a few years
"sniff sniff"There’s nothing confusing about your constant trolling.
“Hoping” being the operative word. Reading some of the comments from other scientists with knowledge of the drug combination, it doesn’t sound like they’re that close, but who knows. If it’s effective and there are no serious side effects, maybe it will be ready that quickly.Your own article said they were hoping to seek FDA approval in 2026
Yeah, the sleepiness during the day was the worst.That would be great. I know a decent number of people that have CPAP machines.
120 events an hour is freaking crazy, that an insanely high number. You must have woken up exhausted, with headaches, and been suffering a ton of other side effects of that.
Oh come on lighten up, it sounds just like something some stupid trump supporting anti vaxxer would say.I think you should find another thread for this nonsense.
Like I said, find another thread. There’s no shortage of threads for the Trump hating cult here.Oh come on lighten up, it sounds just like something some stupid trump supporting anti vaxxer would say.
Is your telling other folks what to do working for you?Like I said, find another thread. There’s no shortage of threads for the Trump hating cult here.
No, because some people just don’t listen to common sense, those would be the ones trolling. Know anyone like that?Is your telling other folks what to do working for you?
I do, how about you?No, because some people just don’t listen to common sense, those would be the ones trolling. Know anyone like that?
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