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And that money fuels the innovation in drug development.American citizens subsidize Big Pharma with tax dollars and pay more for those subsidized drugs than people in other countries.
Shouldn’t that burden be shared by all countries they use the drug?And that money fuels the innovation in drug development.
It wouldn’t happen without that incentive- it just wouldn’t.
That would be nice, but its not. And theres no way to force that to happen.Shouldn’t that burden be shared by all countries they use the drug?
That would be nice, but its not. And theres no way to force that to happen.
But the people in the US are the wealthiest in the world - by far,
when you consider the size. Healthcare becomes more valuable than a fifth television or a second jacked up pickup truck, and we choose to divert the funds to cutting edge medical research- drugs and devices. For certain people at a certain time, having a valuable cancer treatment is more important than anything else in the world. I guess we could direct those funds over to better transportation, or a better military, or a more solid park system, but I think the public prefers cutting edge therapeutics.
Why does Health Care Cost So Much? Musk and Cuban
Cuban laid out seven ways those contracts are keeping drug prices high and hurting employees. His exact list stated:
"All of this allows the big PBMs to continue to distort the pharmacy market for literally EVERYONE," he wrote.
- Don't control your claims data
- Don't control your formulary
- Have to pay more for "Specialty Drugs" that have nothing special about them
- Get rebates that are paid for by your sickest and oldest employees and result in higher deductibles and co-pays that impact the wellness of your workers and their families.
- Cause independent pharmacies to be reimbursed for less than their costs for brand drug scripts for your employees and families, causing them to go out of business.
- Can't talk to manufacturers to put together wellness programs for things like GLP1s.
- Signed a PBM contract with an NDA which prevents you from publicly discussing your PBM contract, resulting in an opaque, inefficient market, which leads to higher prices and lower quality of care for the entire country.
How much does the taxpayer subsidize the development of therapeutics?That would be nice, but its not. And theres no way to force that to happen.
But the people in the US are the wealthiest in the world - by far, when you consider the size. Healthcare becomes more valuable than a fifth television or a second jacked up pickup truck, and we choose to divert the funds to cutting edge medical research- drugs and devices. For certain people at a certain time, having a valuable cancer treatment is more important than anything else in the world. I guess we could direct those funds over to better transportation, or a better military, or a more solid park system, but I think the public prefers cutting edge therapeutics.
Not a huge amount, usually - the government does the basic science research - finds the druggable target molecule. Pharma then finds out how to target the enzyme/receptor, etc with a drug, and brings it through trials. If a compound is discovered by academics, they usually get the patent and any future profits usually go back to the academic institution.How much does the taxpayer subsidize the development of therapeutics?
I read a paper in JAMA on this subject and the paper contends that the NIH spent about $187 billion on drug research into approved drugs from 2010-2019 and that amount was "not less" than what the industry spent.Not a huge amount, usually - the government does the basic science research - finds the druggable target molecule. Pharma then finds out how to target the enzyme/receptor, etc with a drug, and brings it through trials. If a compound is discovered by academics, they usually get the patent and any future profits usually go back to the academic institution.
That study, like most, is messy, because it’s not really clear what ‘development’ means. Having a prodrug that works on a target in cells is not the same as a developed drug.I read a paper in JAMA on this subject and the paper contends that the NIH spent about $187 billion on drug research into approved drugs from 2010-2019 and that amount was "not less" than what the industry spent.
It doesn't seem that the feds concentrate on drugs for rare diseases that won't generate a decent ROI at prices humans can afford because they did research on 90+% of the drugs approved during that time period.
Do I take away from that that "if not for the government the average pharmaceutical would cost twice as much?"
Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry
This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.jamanetwork.com
Shouldn’t that burden be shared by all countries they use the drug?
Some do. Device sales people especially. Pharma - I’d guess 100K.Pharma sales reps in the US make big bucks.
No they dont. Not allowed to do trips- and has been that way for about 20 years. Can’t even hand out pens anymore.They also take groups of doctors on " business trips" to discuss new drugs and or new ways to use older ones.
Not that much anymore. They tend to be people with experience, since the industry has been cut down substantially in the last few decades.Said sales reps are often young and very attractive.
They are large, but the thing is that eliminating those costs will not change a thing on drug development - the investment in sales forces makes the prospect of losing lots of money on an unsuccessful drug worthwhile, because you can really ramp up a successful one.Those costs are likely quite large,
Some do. Device sales people especially. Pharma - I’d guess 100K.
No they dont. Not allowed to do trips- and has been that way for about 20 years. Can’t even hand out pens anymore.
Not that much anymore. They tend to be people with experience, since the industry has been cut down substantially in the last few decades.
They are large, but the thing is that eliminating those costs will not change a thing on drug development - the investment in sales forces makes the prospect of losing lots of money on an unsuccessful drug worthwhile, because you can really ramp up a successful one.
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