Psychedelic compound from magic mushrooms produced in yeast

[JacksinPA]

Psychedelic compound from magic mushrooms produced in yeast

Scientists prove that psilocybin, a potential drug for treating depression and other psychological conditions can be produced in yeast.

www.sciencedaily.com

Psilocybin mushrooms have been found to have minimal harmful effects and could potentially benefit those with depression. But they remain illegal even though they offer a groundbreaking alternative to several under-treated psychological conditions.

Nevertheless, psychedelics are currently riding a wave of positive momentum brought on by cannabis, and if psilocybin gets approved as a pharmaceutical drug, production in yeast appears to be the most commercially viable option.

"It's infeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates. Thus, there is a need to bring down the cost of production and to provide a more consistent supply chain," says Nick Milne, former Postdoc at DTU Biosustain and CSO and Co-founder of Octarine Bio.

Bio-based production of psilocybin has gained big interest and researchers have already proved small-scale production in E. coli. However, production in bacteria comes with a wide range of concerns which can be addressed by using yeast instead.
==================================================================
Coming soon from a factory near you.

 

[Exquisitor]

Whatever happened to the ritual of eating a mushroom?

 

[Threegoofs]

Whatever happened to the ritual of eating a mushroom?

Doesn’t work real well in clinical trials.

 

[Exquisitor]

Doesn’t work real well in clinical trials.

So yeast, how can you screw that up?

 

[Threegoofs]

So yeast, how can you screw that up?

The concept here is that you can standardize the extract and purify the psilocybin, thus knowing precisely what dosage you are giving and standardizing how it’s being absorbed and eliminated. This also allows it to be given in capsule form to allow placebo or an active comparator to be used.

Very convenient to have yeast make the stuff rather than growing mushrooms.

 

[calamity]

Psychedelic compound from magic mushrooms produced in yeast

Scientists prove that psilocybin, a potential drug for treating depression and other psychological conditions can be produced in yeast.

www.sciencedaily.com

Psilocybin mushrooms have been found to have minimal harmful effects and could potentially benefit those with depression. But they remain illegal even though they offer a groundbreaking alternative to several under-treated psychological conditions.

Nevertheless, psychedelics are currently riding a wave of positive momentum brought on by cannabis, and if psilocybin gets approved as a pharmaceutical drug, production in yeast appears to be the most commercially viable option.

"It's infeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates. Thus, there is a need to bring down the cost of production and to provide a more consistent supply chain," says Nick Milne, former Postdoc at DTU Biosustain and CSO and Co-founder of Octarine Bio.

Bio-based production of psilocybin has gained big interest and researchers have already proved small-scale production in E. coli. However, production in bacteria comes with a wide range of concerns which can be addressed by using yeast instead.
==================================================================
Coming soon from a factory near you.

<Goes into kitchen to pull bread out of fridge and sets on counter to let it mold.>

 

[JacksinPA]

<Goes into kitchen to pull bread out of fridge and sets on counter to let it mold.>

Not quite that easy. You would need a starter culture of this genetically modified yeast