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Pre-Clinical Data Shows Cybin’s Novel Analog Could Have Advantages Over Psilocybin

JacksinPA

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While psilocybin has shown significant promise as a potential treatment for mental health conditions like major depressive disorder and anxiety, drug development companies in the psychedelic space like Cybin (NYSE: CYBN) (NEO: CYBN) are working on developing molecules that mimic the drug, but lack some of the constraints of magic mushrooms’ main ingredient.

This morning at the first Microdose: Wonderland conference in Miami, Cybin, the first and only psychedelic company with a NYSE listing, provided a research update pertaining to its proprietary drug, CYB003. The company says it possesses “multiple advantages” over classic psilocybin molecules.

Though safe, Cybin suggests that in a clinical context, classic psilocybin has limitations, including a long duration (around six hours), a long onset until effects are felt (about 45 minutes), and high variability from patient to patient.
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I don't recall seeing this before. Tis article could have used an editor that knew something about drug chemistry. For instance, psilocybin is a molecule & not plural. It refers to this new drug to have several advantages over natural psilocybin but only describes its chemistry as 'deuterated psilocybin.' Hope I run into more on this as I would think that just substituting deuterium for one or more hydrogen atoms would not have this kind of biological effect.
 

While psilocybin has shown significant promise as a potential treatment for mental health conditions like major depressive disorder and anxiety, drug development companies in the psychedelic space like Cybin (NYSE: CYBN) (NEO: CYBN) are working on developing molecules that mimic the drug, but lack some of the constraints of magic mushrooms’ main ingredient.

This morning at the first Microdose: Wonderland conference in Miami, Cybin, the first and only psychedelic company with a NYSE listing, provided a research update pertaining to its proprietary drug, CYB003. The company says it possesses “multiple advantages” over classic psilocybin molecules.

Though safe, Cybin suggests that in a clinical context, classic psilocybin has limitations, including a long duration (around six hours), a long onset until effects are felt (about 45 minutes), and high variability from patient to patient.
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I don't recall seeing this before. Tis article could have used an editor that knew something about drug chemistry. For instance, psilocybin is a molecule & not plural. It refers to this new drug to have several advantages over natural psilocybin but only describes its chemistry as 'deuterated psilocybin.' Hope I run into more on this as I would think that just substituting deuterium for one or more hydrogen atoms would not have this kind of biological effect.

I don't know about the chemistry, and I usually prefer natural products, but if they could give me a faster onset, shorter term psychedelic experience, I'd try it.
 
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