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Inside the body, the coronavirus is even more sinister than scientists had realized

minnie616

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There is still much to be learned about Covi 19

The experts are still surprised how sinister and different this virus is than other viruses.

Inside the body, the coronavirus is even more sinister than scientists had realized

The new coronavirus’ reputation for messing with scientists’ assumptions has taken a truly creepy turn.

Researchers exploring the interaction between the coronavirus and its hosts have discovered that when the SARS-CoV-2 virus infects a human cell, it sets off a ghoulish transformation. Obeying instructions from the virus, the newly infected cell sprouts multi-pronged tentacles studded with viral particles.

These disfigured zombie cells appear to be using those streaming filaments, or filopodia, to reach still-healthy neighboring cells. The protuberances appear to bore into the cells’ bodies and inject their viral venom directly into those cells’ genetic command centers — thus creating another zombie.

The authors of the new study, an international team led by researchers at UC San Francisco, say the coronavirus appears to be using these newly sprouted dendrites to boost its efficiency in capturing new cells and establishing infection in its human victims.

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Inside the body, the coronavirus is even more sinister than scientists had realized
 
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minnie616

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Our experts generally suck, so naturally.....

Perhaps you should have read a bit more of the article.

They are hopeful several cancer drugs may be useful as treatments for Covid 19.

The scientists also believe they have identified several drugs that could disrupt the viral takeover of cells and slow the process by which COVID-19 takes hold. These compounds, many of which were designed as cancer treatments, seem likely to work because they block the chemical signals that activate filopodia production in the first place.

Among the seven drugs they identified as potentially useful against COVID-19 are Silmitasertib, a still-experimental drug in early clinical trials as a treatment for bile duct cancer and a form of childhood brain cancer; ralimetinib, a cancer drug developed by Eli Lilly; and gilteritinib (marketed as Xospata), a drug in use already to treat acute myeloid leukemia.

The new research emerges from an ambitious effort to identify promising COVID-19 treatments using the science of “proteomics,” the interactions among proteins. Scientists set out to identify the chemical signals and cascading chain of events that take place when a virus meets and overtakes a host cell. Then, they look for drug compounds that could scramble those chemical signals and disrupt the process of infection.

Until now, the process by which the coronavirus was thought to infect cells was pretty run-of-the-mill for a virus: It found receptors on the surface of the cells that line humans’ mouth, nose, respiratory tract, lungs and blood vessels.

Like space invaders in a science fiction tale, the tiny virus was known to dock on the surface of the much larger cell.

Inside the body, the coronavirus is even more sinister than scientists had realized
 
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