Technocratic_Utilitarian
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There's nothing wrong with using laboratory animals for experiments on several grounds.
1. Utility ethics/personhood
2. Pragmaticism
Pragmaticism is important because it limits ethics. First, look at why it is intrinsically ok to use animals sometimes and when it is not ok to use animals sometimes. I then establish how this intrinsic "ok" is molded and changed due to pragmatic concerns. Even if something would be ideally ethical, you cannot always apply it perfectly in reality.
1. Generally, you ought to do what does the greatest god. If the choice of using lab animals over humans maximizes necessary benefits and minimizes necessary harms, you ought to choose lab animals. I support animal testing for medicine and things that objectively benefit the whole. I have no problem with testing on animals who are not sapient for medical purpouses, but I do not support experiments for "cosmetic research." However, in the interest of justice, all sentient animals should be given some moral consideration if it is given that they have roughly equal mental faculties to a human. deally, for all animals that have relative par with humans mentally, you should treat them no differently from a similiar level human. To accentuate this, you should not do an experiment on X animal if you would not do said experiment on Y human with the same rough mental capacity. For example, if you have an extremely retarded infant or a really low IQ human, and you want to test the effectiveness on it or a chimp, you shouldn't do the test on the chimp if you wouldn't do it on the baby human as well, given that the baby is at a mental level equal to or lower than the chimp. That is very possible. Once establishing this concept, we can move to pragmatism and see that even if this were true, utility is also influenced by what can actually be done reasonably.
2. Even if you accept that you shouldn't be speciest, there are some pragmatic concerns which make other animals very useful, whereas using human equivalents wouldn't be. If there is some extrinsic reason for not so being "just," you can add utility on behalf of using the other animals. Using retarded babies for testing chemicals, drugs, etc might or might not work. If you are testing for drugs, it's possible that the drug might work differently for retarded kids. There would be a drop in Utility if you used the human because of inaccuracies. If these inaccuracies would be minimal, however, then it's not a problem.
Another pragmatic concern is not effectiveness of experiments and tests, rather supply. It seems like it would be very expensive to get a large supply of babies. You would have to have some type of baby-factory suppllying severely retarded babies; that's not bad in and of itself, but the cost would probably be undoable. Rats and other animals can be gotten cheaply, and you need lots of them to have successful results.
However, there's nothing wrong, really, with testing on human subjects such as prisoners, given that they are going to die anyway, whether they want to be tested on or not. It's really irrelevant what their sapience-status is if you are going to kill them regardless. You might as well kill them and do good instead of killing them and wasting money. However, if they aren't going to die, and killing them isn't already going to happen, then morality would shift back to animals.
1. Utility ethics/personhood
2. Pragmaticism
Pragmaticism is important because it limits ethics. First, look at why it is intrinsically ok to use animals sometimes and when it is not ok to use animals sometimes. I then establish how this intrinsic "ok" is molded and changed due to pragmatic concerns. Even if something would be ideally ethical, you cannot always apply it perfectly in reality.
1. Generally, you ought to do what does the greatest god. If the choice of using lab animals over humans maximizes necessary benefits and minimizes necessary harms, you ought to choose lab animals. I support animal testing for medicine and things that objectively benefit the whole. I have no problem with testing on animals who are not sapient for medical purpouses, but I do not support experiments for "cosmetic research." However, in the interest of justice, all sentient animals should be given some moral consideration if it is given that they have roughly equal mental faculties to a human. deally, for all animals that have relative par with humans mentally, you should treat them no differently from a similiar level human. To accentuate this, you should not do an experiment on X animal if you would not do said experiment on Y human with the same rough mental capacity. For example, if you have an extremely retarded infant or a really low IQ human, and you want to test the effectiveness on it or a chimp, you shouldn't do the test on the chimp if you wouldn't do it on the baby human as well, given that the baby is at a mental level equal to or lower than the chimp. That is very possible. Once establishing this concept, we can move to pragmatism and see that even if this were true, utility is also influenced by what can actually be done reasonably.
2. Even if you accept that you shouldn't be speciest, there are some pragmatic concerns which make other animals very useful, whereas using human equivalents wouldn't be. If there is some extrinsic reason for not so being "just," you can add utility on behalf of using the other animals. Using retarded babies for testing chemicals, drugs, etc might or might not work. If you are testing for drugs, it's possible that the drug might work differently for retarded kids. There would be a drop in Utility if you used the human because of inaccuracies. If these inaccuracies would be minimal, however, then it's not a problem.
Another pragmatic concern is not effectiveness of experiments and tests, rather supply. It seems like it would be very expensive to get a large supply of babies. You would have to have some type of baby-factory suppllying severely retarded babies; that's not bad in and of itself, but the cost would probably be undoable. Rats and other animals can be gotten cheaply, and you need lots of them to have successful results.
However, there's nothing wrong, really, with testing on human subjects such as prisoners, given that they are going to die anyway, whether they want to be tested on or not. It's really irrelevant what their sapience-status is if you are going to kill them regardless. You might as well kill them and do good instead of killing them and wasting money. However, if they aren't going to die, and killing them isn't already going to happen, then morality would shift back to animals.