Early findings show new drug could be ‘gamechanging’ for brain cancer treatment

[JacksinPA]

Early findings show new drug could be ‘gamechanging’ for brain cancer treatment

Using ipatasertib, researchers say some brain cancers could potentially be made vulnerable to immunotherapy agent

www.theguardian.com

Using ipatasertib, researchers say some brain cancers could potentially be made vulnerable to immunotherapy agents.

Two people with advanced brain cancer of the sort that led to the death of the MP Tessa Jowell have responded well in a small trial to an experimental combination of chemo and immunotherapy drugs. In one case, the life-threatening tumour seems to have disappeared.

Doctors at the Institute of Cancer Research and the Royal Marsden hospital in London cautioned that this was very early research but said it was unusual to have such a good response in patients in an early trial.

Ten patients were enrolled in the phase I trial called Ice-Cap. They had advanced glioblastoma, a tumour in the brain similar to that which also killed US president Joe Biden’s son, Beau.
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I had a former business associate die of inoperable brain cancer. He was a former Marine & exercised a lot. While I hated his guts, this is no way to die.

 

[JacksinPA]

Early findings show new drug could be ‘gamechanging’ for brain cancer treatment

Using ipatasertib, researchers say some brain cancers could potentially be made vulnerable to immunotherapy agent

www.theguardian.com

Using ipatasertib, researchers say some brain cancers could potentially be made vulnerable to immunotherapy agents.

Two people with advanced brain cancer of the sort that led to the death of the MP Tessa Jowell have responded well in a small trial to an experimental combination of chemo and immunotherapy drugs. In one case, the life-threatening tumour seems to have disappeared.

Doctors at the Institute of Cancer Research and the Royal Marsden hospital in London cautioned that this was very early research but said it was unusual to have such a good response in patients in an early trial.

Ten patients were enrolled in the phase I trial called Ice-Cap. They had advanced glioblastoma, a tumour in the brain similar to that which also killed US president Joe Biden’s son, Beau.
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I had a former business associate die of inoperable brain cancer. He was a former Marine & exercised a lot. While I hated his guts, this is no way to die.

This is a small molecule under development by the huge Swiss pharma company Roche. It is also in trials (phase II) for breast cancer.

My wife is a breast cancer survivor. I hope I don't have to go through that (chemo + surgery).