- Dec 3, 2017
- Reaction score
- Political Leaning
COVID-19: Tannic acid targets key stages in the fight against SARS-CoV-2 infection
Natural polyphenol seems to inhibit the activity of three important molecular pathways involved in the SARS-CoV-2 infection
Professor Charles Ramassamy and his postdoctoral researcher Mohamed Haddad at Institut national de la recherche scientifique (INRS), in collaboration with scientists from Université de Montréal, McGill University, and Université du Québec à Montréal (UQAM), believe that tannic acid plays a role in inhibiting three important molecular pathways involved in the SARS-CoV-2 infection. Their work was published recently in the International Journal of Molecular Sciences (IJMS).
Using a multidisciplinary approach, the teams showed that tannic acid inhibits the viral protein (RBD) of the British variant of SARS-CoV-2 from binding to its biological target, the ACE2 receptor. This receptor, which is found on the surface of many cells in the body, allows the virus to latch on and infect them. "Tannic acid binds to the RBD protein and prevents it from binding to the ACE2 receptor," said Professor Ramassamy. He explained that in blocking the viral protein, tannic acid does not alter the physiological functions of ACE2 receptors, which have physiological functions in the body's respiratory, cardiovascular, and renal systems, among others.
I did a lot of research into COVID inhibitors & found that several polyphenolic chemicals found in plants work in this role. A polyphenolic is an aromatic molecule with more than one phenolic hydroxyl group.
What is advertised on Amazon as lab-grade tannic acid is caveat emptor. This post is not an ad for this stuff.