- Joined
- Jan 20, 2020
- Messages
- 741
- Reaction score
- 154
- Gender
- Male
- Political Leaning
- Centrist
Study found that mRNA Vaccines suppress your Innate Immune and can cause disastrous consequences
https://www.authorea.com/users/4555...role-of-g-quadruplexes-exosomes-and-micrornas
https://www.authorea.com/users/4555...role-of-g-quadruplexes-exosomes-and-micrornas
The mRNA vaccines utilize genetically modified mRNA encoding spike proteins. These alterations hide the mRNA from cellular defenses, promote a longer biological half-life for the proteins, and provoke higher overall spike protein production. However, both experimental and observational evidence reveals a very different immune response to the vaccines compared to the response to infection with SARS-CoV-2. As we will show, the genetic modifications introduced by the vaccine are likely the source of these differential responses. In this paper, we present the evidence that vaccination, unlike natural infection, induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health.
All of these observations are consistent with the idea that the vaccines actively suppress type I IFN signaling, as we will discuss below.
Impaired type I IFN signaling is linked to many disease risks, most notably cancer, as type I IFN signaling suppresses proliferation of both viruses and cancer cells by arresting the cell cycle
For example, Bidwell et al. (2012) found that, among over 800 breast cancer patients, those with high expression of IRF7-regulated genes had significantly fewer bone metastases
IRF9, too, has a central role to play in cancer surveillance and prevention.
Thus, the exceedingly important cancer regulatory genes BRCA1 and BRCA2 rely on IRF7 and IRF9, respectively, to carry out their protective effects.
Vaccination has also been demonstrated to suppress both IRF7 and STAT2 [52]. This can be expected to interfere with the cancer-protective effects of BRCA1 as described above. Cancers associated with impaired BRCA1 activity include breast, uterine, and ovarian cancer in women; prostate and breast cancer in men; and a modest increase in pancreatic cancer for both men and women [53].
Reduced BRCA1 expression is linked to both cancer and neurodegeneration.
Given the universally recognized importance of optimally functioning BRCA1/2 for cancer prevention and given the central role of the TRAIL signal transduction pathway for additional cancer surveillance, the suppression of IRF7 and IRF9 through vaccination and subsequent spike protein production is extremely concerning for long-term cancer control in injected populations.
A breakthrough came when it was discovered experimentally that the mRNA coding for the spike protein could be modified in specific ways that would essentially fool the human cells into recognizing it as harmless human RNA.
A seminal paper by Karikó et al. (2005) demonstrated through a series of in vitro experiments that a simple modification to the mRNA such that all uridines were replaced with pseudouridine could dramatically reduce innate immune activation against exogenous mRNA [59]. Andries et al. (2015) later discovered that 1-methylpseudouridine as a replacement for uridine was even more effective than pseudouridine and could essentially abolish the TLR response to the mRNA, preventing the activation of blood-derived dendritic cells [61]. This modification is applied in both the mRNA vaccines on the market [62].
(PDF) Innate Immune Suppression by SARS-CoV-2 mRNA Vaccinations: The role of G-quadruplexes, exosomes and microRNAs
PDF | The mRNA SARS-CoV-2 vaccines were brought to market in response to the widely perceived public health crises of Covid-19. The utilization of mRNA... | Find, read and cite all the research you need on ResearchGate
www.researchgate.net